Protein_Domain
nikABCDE

Part:BBa_K2652006

Designed by: Siyun Xiong   Group: iGEM18_HBUT-China   (2018-10-12)
Revision as of 14:02, 12 October 2018 by Registry (Talk | contribs)

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Nickel ion channel protein gene

NikA is in the periplasm between the cell membrane and the cell wall. It can capture and bind to free nickel ions and transport it to NikB and NikC located on the cell membrane. NikB and NikC have binding sites for nickel ions. NikD and NikE can be combined with ATP provides energy for the transport of nickel ions. When ATP is not bound, the binding site of nickel ion is exposed to the outside of the cell membrane. After ATP binding, the protein structure of NikB and NikC changes, and the binding site of nickel ion is transferred to the intracellular measurement, thereby completing the transmembrane transport of nickel ions.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 1560
    Illegal AgeI site found at 3561
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None