Coding
Part:BBa_K2570016:Design
Designed by: Xueyi Yang Group: iGEM18_FJNU-China (2018-09-30)
hns
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 154
Design Notes
H-NS is a global-regulated protein which could bind to genome and specifically inhibit proU. We did site-directed mutation for hns in order to meet the requirements of RFC10. Detailed information in BBa_K2570011
Source
E.coli K12.
References
[1]Interactions of the Nucleoid-associated DNA-binding Protein H –NS with the Regulatory Region of the Osmotically Controlled proU Operon of Escherichia coli* The JOUTNAL OF BIOLOGICAL CHEMISTRY, April 1994