Composite
crRNA-rrnB
Part:BBa_K2627004:Design
Designed by: Zhaoqin Zhang Group: iGEM18_SDU-CHINA (2018-10-06)
crRNA targeting GltA
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 314
Design Notes
We managed to delete the restriction site for EcoRI through Gibson Assembly.
Source
Chang, Y., et al., Easy regulation of metabolic flux in Escherichia coli using an endogenous type I-E CRISPR-Cas system. Microbial Cell Factories, 2016. 15(1).