Part:BBa_K2471013
N-acyl homoserine lactonase from Bacillus sp. A24
This aiiA gene comes from Bacillus sp. 240B1. Expression of aiiA in transformed Erwinia carotovora strain SCG1 significantly reduced the release of autoinducers, decreased extracellular pectolytic enzyme activities, and attenuated pathogenicity on potato, eggplant, chinese cabbage, carrot, celery, cauliflower, and tobacco. The successful degradation of AHLs makes this gene a great alternative to inhibit several of the virulence factors from Erwinia amylovora. The results given by Dong et al. encouraged the potential applications of this gene in the future, “Our results show that the aiiA gene product inhibits virulence of E. carotovora when expressed in the pathogen” (Dong, et al., 2000).
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
None |