Composite
Part:BBa_K2467003:Design
Designed by: Alreem Johar Group: iGEM17_CMUQ (2017-10-26)
WT proU-RBS-mRFP-B0015
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 857
Illegal AgeI site found at 969 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
The sensor will induce expression of RFP when osmolarity is high. The sensor can be utilized to measure salt concentrations to determine if the SRB can survive. The promoter can then be used to produce the dispersin enzyme to degrade the biofilm where the SRB accumulate and corrode the pipes.
Source
Escherichia coli proU operon
References
May G, Faatz E, Lucht JM, Haardt M, Bolliger M, Bremer E. 1989. Characterization of the osmoregulated Escherichia coli proU promoter and identification of ProV as a membrane-associated protein G. Mol Microbiol 3:1521-1531.