Part:BBa_K2317001:Design

CbtA

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]

Design Notes

This is a protein without any tag.

Source

sequenced genome of E.coli str. K-12

References

1、Page, R.; Peti, W. Toxin-antitoxin systems in bacterial growth arrest and persistence. Nat. Chem. Biol. 2016, 12, 208–214.

               2、Nathalie Goeders ， Laurence Van Melderen*（2014）Toxin-Antitoxin Systems as Multilevel Interaction SystemsToxins (Basel). 2014 Jan; 6(1): 304–324.

               3、Yamaguchi Y, Park J H, Inouye M. Toxin-antitoxin systems in bacteria and archaea[J]. Annual review of genetics, 2011, 45: 61-79.

               4、Masuda, H.; Tan, Q.; Awano, N.; Wu, K.; Inouye, M. YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli. Mol. Microbiol. 2012, 84, 979–989.

               5、Tan Q, Awano N, Inouye M. YeeV is an Escherichia coli toxin that inhibits cell division by targeting the cytoskeleton proteins, FtsZ and MreB[J]. Molecular microbiology, 2011, 79(1): 109-118.

               6、 Yamaguchi Y, Inouye M. mRNA Interferases, Sequence‐Specific Endoribonucleases from the Toxin–Antitoxin Systems[J]. Progress in molecular biology and translational science, 2009, 85: 467-500.

               7、Heller D M, Tavag M, Hochschild A. CbtA toxin of Escherichia coli inhibits cell division and cell elongation via direct and independent interactions with FtsZ and MreB[J]. PLoS Genetics, 2017, 13(9): e1007007.

               8、Van den Ent F, Izoré T, Bharat T A M, et al. Bacterial actin MreB forms antiparallel double filaments[J]. Elife, 2014, 3: e02634.