Composite
Part:BBa_K2374007
Designed by: Jianfeng Zhou Group: iGEM17_Tongji_China (2017-10-26)
UAS-TH -> (fruit fly)
ple (Tyrosine 3-monooxygenase, TH)
ple (TH) is a rate-limiting enzyme in the dopamine’s synthesis, and it plays an important role in the physiology of adrenergic neurons.
Catalytic activity:
L-tyrosine + tetrahydrobiopterin + O2 = L-dopa + 4a-hydroxytetrahydrobiopterin.
This subpathway is part of the pathway dopamine biosynthesis, which is itself part of catecholamine biosynthesis.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal PstI site found at 13
Illegal PstI site found at 256 - 12INCOMPATIBLE WITH RFC[12]Illegal PstI site found at 13
Illegal PstI site found at 256 - 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 1540
Illegal XhoI site found at 672 - 23INCOMPATIBLE WITH RFC[23]Illegal PstI site found at 13
Illegal PstI site found at 256 - 25INCOMPATIBLE WITH RFC[25]Illegal PstI site found at 13
Illegal PstI site found at 256 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 918
Illegal BsaI site found at 1884
Illegal BsaI.rc site found at 636
Illegal BsaI.rc site found at 1402
Illegal BsaI.rc site found at 1551
[edit]
Categories
Parameters
None |