Part:BBa_K2520043

Celiac epitope 1

Celiac

Celiac is a long term autoimmune disorder affecting the internal intestine that is caused due to T cells attacking the Gliadin which is absorbed in the inner wall cells of the small intestine. Gliadin is one of a two proteins that forms gluten. This process leads to severe inflammation, and thus interferes with the absorption of food and greatly increases the chances of contracting colorectal cancer. The prevalence of celiac disease is approximately 0.5% -1% in different parts of the world. The only treatment that eliminates all symptoms (but does not cure the disease) is a strict avoidance of foods containing gluten.

References

(1) Gujral, Naiyana, Hugh J. Freeman, and Alan BR Thomson. "Celiac disease: prevalence, diagnosis, pathogenesis and treatment." World journal of gastroenterology: WJG 18.42 (2012): 6036.‏ Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]