Coding
Part:BBa_K2271105:Design
Designed by: Manuel Lentzen Group: iGEM17_Cologne-Duesseldorf (2017-10-27)
PEX5 variant R15
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 409
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This part is based on the yeasts PEX5 gene. In the course of a targeted mutagensis approach this PEX5 variant was designed to interact with a non-native PTS1 sequence. We verified that this variant does not detect the wildtype PTS1 but our designed PTS1* and leads to the import of the protein attached to it. We thereby provide a construct which allows full control over the peroxisomes protein contents.
Source
Synthesized by IDT.