Coding

Part:BBa_K2486105

Designed by: Tiago Lubiana Alves   Group: iGEM17_USP-Brazil   (2017-10-27)
Revision as of 00:10, 28 October 2017 by Lubdub (Talk | contribs)


West Nile Virus entry blocking WNV-Domain III protein

[theoretical part] [not assembled, not synthesized, not sent, not characterized]


Peptide from West Nile Virus capsid able to block, by competition, its binding to insect cells. Could be able to reduce infectivity rates in the mosquito

Aminoacids 299-401 from http://www.uniprot.org/uniprot/Q91R00. Sequence codon optized to E. coli with https://www.idtdna.com/CodonOpt

Isaacs, Alison T., et al. "Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi." PLoS pathogens 7.4 (2011): e1002017.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None