Coding
Part:BBa_K2382015:Design
Designed by: HO-LO HUANG Group: iGEM17_CSMU_NCHU_Taiwan (2017-10-26)
Thioredoxin-FGD fusion protein
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NotI site found at 1030
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 1079
Illegal BamHI site found at 367
Illegal XhoI site found at 373
Illegal XhoI site found at 1345 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 739
Illegal NgoMIV site found at 937
Illegal AgeI site found at 703 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
The usage of thioredoxin is to make FGD more soluble. However we don't want the two small protein to interrupt the folding of each other. That's why we add some linkers between them.
Source
thioredoxin Escherichia coli str. K-12 substr. MG1655 ( NC_000913.3 )
FGD Mycobacterium smegmatis str. MC2 155 (AAC38338.1)