Part:BBa_K2302004
L-FABP,a protein that can bind long chain fatty acids.
This sequence encodes a functional protein, liver fatty acid binding protein (L-FABP), which is one of fatty acid binding proteins with a molecular weight of 14-15 kDa.[1] It can reversibly bind long chain fatty acids with hydrogen bond. Its structure consists of two β-sheets, capped by a helix-turn-helix motif. The β-strands are organized into a β-barrel configuration, forming a clam-like structure that encloses a large solvated cavity to form a ligand binding site.[2]FABP1 is primarily expressed in the liver where it is involved in the binding, transport and metabolism of long-chain fatty acids (LCFAs), endocannabinoids, phytocannabinoids, synthetic cannabinoid receptor (CBR) agonists and antagonists, and other hydrophobic molecules.[3]
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 214
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