Composite
FrmRS

Part:BBa_K2257007:Hard Information

Designed by: Ruoyun Wang   Group: iGEM17_Nanjing-China   (2017-10-22)
Revision as of 13:28, 25 October 2017 by Linyumeng (Talk | contribs) (Description)

   Protein FrmR acts as a regulator, it can form DNA-protein cross-links with a special promotor PfrmAB to prevent activating downstream gene transcription  

Formaldehyde is able to covalently modify protein FrmR, inhibiting its function, so when formaldehyde exists, promotor PfrmAB is capable of activating downstream gene transcription by the destruction of the promoter PfrmAB- the protein FrmRcross-link.