Coding
Part:BBa_K2255006:Design
Designed by: Hussein Daher Group: iGEM17_Aix-Marseille (2017-08-28)
EPS-Depolymerase (Rfc25)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The protein is 852 amino acid with is translated to 2556 nucleobases is quite big making it difficult to work with so a process of trimming was donne. Seeing as the domain we are interested in pectin lyase start from the 139th to 426th amino acid it is possible to remove the excess amino acids without harming the functionality and specificity of the enzyme.
Source
Genomic sequence from the phage vB_XveM_DIBBI