Part:BBa_K1976048

Colicin E2 DNase domain "miniColicin"

Colicin E2 is a peptide, that is toxic to coliform bacteria. It is one of a group of proteins of this type, it being a nicking endonuclease. It has a corresponding activity inhibiting protein called immunity protein Im2, which is also in the registry under the name .

Figure 1:Structure of Colicin E2 DNase domain derived from a molecular dynamics simulation.

Usage

The Colicin E2 immunity protein (BBa_K1976027 and BBa_K1976028) can be used in combination with the Colicin E2 DNase.

Characteristics

Molecular Weight	15.2 kDa
Residues	133
pI	9.06
[Data taken created in Snapgene and http://isoelectric.ovh.org/calculate.php]

References
[1] Cascales et al, Colicin Biology, Microbiology and Molecular Biology Reviews, vol. 71, pp. 158-229, 2007