Coding

Part:BBa_K1961007

Designed by: Yi-Ting Lin   Group: iGEM16_HSiTAIWAN   (2016-10-12)
Revision as of 08:14, 23 October 2016 by Jonathan0912 (Talk | contribs)


CYP1A2, an enzyme of cytochrome P450 protein family that metabolizes toxin in liver

The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1A2 is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include aflatoxin B1, and acetaminophen.


alt text


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 1400
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 320
    Illegal NgoMIV site found at 407
    Illegal AgeI site found at 390
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 1120


[edit]
Categories
Parameters
None