Composite
CiproR

Part:BBa_K1930004

Designed by: Mareike Schmidt   Group: iGEM16_Groningen   (2016-10-16)
Revision as of 23:21, 16 October 2016 by Barawaclawik (Talk | contribs)


Ciprofloxacin resistance cassette

This part is a fluoroquinolone resistance gene qnrS1. This gene is found naturally in E. coli, and other Gram-negative strains. qnr genes code for pentapeptide repeat proteins. These proteins reduce susceptibility to quinolones by protecting the complex of DNA and DNA gyrase enzyme from the inhibitory effect of quinolones. 

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 536
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//cds/selectionmarker/antibioticresistance
//chassis/prokaryote/bsubtilis
//chassis/prokaryote/ecoli
Parameters
function
resistance