Coding
CCR7

Part:BBa_K1993001

Designed by: Su Xiaojun   Group: iGEM16_SYSU-MEDICINE   (2016-10-08)
Revision as of 15:58, 15 October 2016 by LittleCloud (Talk | contribs)


CCR7


Chemokine receptors are found on the surface of certain cells that interact with chemokines. They have a 7-transmembrane (7TM) structure and couples to G-protein for signal transduction within a cell[1] (Figure 1). Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux inintracellular calcium (Ca2+) ions which initiate the onset of chemotaxis that traffics the cell to a desired location (Figure 2).


File:T--SYSU-MEDICINE--Chemokine receptors.png

Figure 1. typical structure of a chemokine receptor.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 1111
    Illegal SapI site found at 1017


[edit]
Categories
//collections/immune_regulation/receptors
Parameters
None