Coding
Si-tag2
Part:BBa_K1592008:Design
Designed by: Shuyan Tang Group: iGEM15_HUST-China (2015-09-06)
Revision as of 04:46, 17 September 2015 by WangjieLiu (Talk | contribs)
LIP prepro + E. coli ribosomal protein L2 (61-202aa) + YLcwp3 Fusion
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 100
Illegal XhoI site found at 620 - 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI site found at 641
Design Notes
In order to replace the domains more conveniently, we added BamHI, SalI, NdeI, NdeI between LIP2 prepro, E. coli ribosomal protein L2(61-222aa), GS linker and YLcwp3.Also we added 6Xhis-tag between LIP2 prepro and E. coli ribosomal protein L2 (61-222aa) to do verification of immunofluorescence.
Source
E. coli ribosomal protein L2 was synthesized by IDT, LIP2 prepro and YLcwp3 were cloning from the plasmid JMP62, and we fused this three sequences.