Regulatory
Part:BBa_K1699001:Design
Designed by: Emil Ruvinov Group: iGEM15_BGU_Israel (2015-08-09)
Human short TERT promoter
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Cloned into pSB1C3 using EcoRI and PstI restrictoion sites.
Source
Human genomic DNA sequence. Based on: Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers. Gu J, Kagawa S, Takakura M, Kyo S, Inoue M, Roth JA, Fang B. Cancer Res. 2000 Oct 1;60(19):5359-64. http://www.ncbi.nlm.nih.gov/pubmed/11034071