Composite
Part:BBa_K1714000
Designed by: Hiroki ONO Group: iGEM15_HokkaidoU_Japan (2015-09-10)
pBad/araC-RBS B0034-Ag43 thanatin as alpha domain-double terminator
Ag43 is a kind of outer membrane protein that is composed of 3 domains. First one is signal peptide that transport Ag43 to outer membrane. Second one is alpha domain that has connection peptide to another Ag43 alpha domain. Last one is beta domain that has beta barrel structure to let the barrel there. This part has thanatin, a kind of antimicrobial peptide as alpha domain. This thanatin has Asp as the last residue. So if thanatin domain is digested by Asp-N endoproteinase (NEB), this part secrets thanatins.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 1205
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 1468
Illegal BamHI site found at 1144 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1750
Illegal NgoMIV site found at 2260
Illegal NgoMIV site found at 2281
Illegal AgeI site found at 979
Illegal AgeI site found at 1413
Illegal AgeI site found at 2020
Illegal AgeI site found at 2434
Illegal AgeI site found at 2676 - 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI site found at 961
[edit]
Categories
Parameters
//collections/antimicrobial
None |