Device

Part:BBa_K1613007

Designed by: Ko-yu Chang   Group: iGEM15_HSNU-TAIPEI   (2015-09-05)
Revision as of 03:27, 6 September 2015 by Registry (Talk | contribs)

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A composite part that can detect some toxins.

cyp1a2 can oxidize the substances that it can metabolism. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1A2 is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include aflatoxin B1, and acetaminophen.


Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal prefix found in sequence at 64
    Illegal suffix found in sequence at 1653
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 64
    Illegal NheI site found at 7
    Illegal NheI site found at 30
    Illegal SpeI site found at 1654
    Illegal PstI site found at 1668
    Illegal NotI site found at 70
    Illegal NotI site found at 1661
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 64
    Illegal BglII site found at 1483
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal prefix found in sequence at 64
    Illegal suffix found in sequence at 1654
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal prefix found in sequence at 64
    Illegal XbaI site found at 79
    Illegal SpeI site found at 1654
    Illegal PstI site found at 1668
    Illegal NgoMIV site found at 403
    Illegal NgoMIV site found at 490
    Illegal AgeI site found at 473
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 1203


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Parameters
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