Coding
Part:BBa_K1323012
Designed by: Julia Manalil Group: iGEM14_Waterloo (2014-10-04)
Spc - Spectinomycin Resistance Gene Coding Sequence
This coding sequence is for the antibiotic spectinomycin. The sequence of this gene is obtained from pSPC vector developed by Dr. Jeffery Bose (KUMC) and Dr. Kenneth Bayles (NUMC) (Bose et al., 2013). The 618 bp of the CDS was changed from T to A to eliminate illegal pst1 site. The working concentration of spectinomycin of 1000 µg/mL in S.aureus/S.epidermidis hosts (Bose et al., 2013).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 488
References
Bose, J. L., Fey, P. D., and Bayles, K. W. (2013). Genetic Tools to Enhance the Study of Gene Function and Regulation in Staphylococcus aureus. Applied and Environmental Microbiology. 79 (7): 2218-2224.
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Categories
Parameters
//cds/selectionmarker/antibioticresistance
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