Part:BBa_K1510002

PnlmC (S.mutans)

This part is derived from Streptococcus mutans UA159, a gram positive bacterium. According to study done by Liu et al.[http://link.springer.com/article/10.1007%2Fs13213-013-0629-6 Liu, T., et al., ComCED signal loop precisely regulates nlmC expression in Streptococcus mutans. Annals of Microbiology, 2014. 64(1): p. 31-38.], nlmC promoter can sense competence stimulating peptide (CSP).As a result, the main function of this promoter is to sense a quorum sensing chemical, competence-stimulating peptide (CSP), and trigger down string gene.

The picture is derived from the study done by Liu et al., indicating the CSP stimulation of nlmC promoter.

[http://link.springer.com/article/10.1007%2Fs13213-013-0629-6 Liu, T., et al., ComCED signal loop precisely regulates nlmC expression in Streptococcus mutans. Annals of Microbiology, 2014. 64(1): p. 31-38.]

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]