Coding
Part:BBa_K1420001
Designed by: Stephen C. Heinsch Group: iGEM14_Minnesota (2014-09-26)
merA, mercuric reductase from Serratia marcescens
Function
Mercury resistant genemerA encodes a a mercuric ion reductase (MerA) that catalyze the reduction of mercuric ion(Hg2+) to the relative inert, volatile monoatomic mercury (Hg0) in a NADPH dependent reaction. While orchestrating with the transportation system composed of other gene products of Mer Operon, MerA and MerB are the key detoxification enzymes that confer mercury resistance. Scheme 1. MerA Catalyzed Reaction <p>
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Structure and Mechanism
Zone of Inhibition Results
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1201
Illegal NgoMIV site found at 1249
Illegal NgoMIV site found at 1311
Illegal NgoMIV site found at 1522 - 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
//binding/metal
//cds
//cds
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