RNA
Part:BBa_K1223014
Designed by: Orr Schlesinger Group: iGEM13_BGU_Israel (2013-10-03)
tRNA-Pyl (pylT) gene from Methanosarcina barkeri str. Fusaro
this is the DNA coding sequence for the tRNA of pyrrolysine from the Archaea Methanosarcina barkeri str. Fusaro.
this tRNA is a part of the machinery that is used to incorporate pyrolysine into proteins in E.coli.
the tRNA synthetase that charges the tRNA with pyrrolysine can be found in biobrick BBa_k1223013.
the tRNA has the anticodon CUA - which means that the sense codon needed to incorporate pyrrolysine is TAG - the amber stop codon.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
function | tRNA |
ligands | pyrrolysine, propargyl-lysine |
strain | Methanosarcina barkeri str. Fusaro |