Part:BBa_K1230001:Design
LL-37 antimicrobial peptide
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Addition of initiation and stop codons.
Source
Synthesis from genscript
References
1. Zhang L, Yu J, Wong CC, Ling TK, Li ZJ, Chan KM, Ren SX, Shen J, Chan RL, Lee CC. Cathelicidin protects against Helicobacter pylori colonization and the associated gastritis in mice. Gene Ther. 2012;:Dec 20;. 2. Hase K, Murakami M, Iimura M, Cole SP, Horibe Y, Ohtake T et al. Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. Gastroenterology 2003; 125: 1613–1625. 3. J. Krahulec, M. Hyršová, S. Pepeliaev, J. Jílková, Z. Cerny ́, J. Machálková, High level expression and purification of antimicrobial human cathelicidin LL-37 in Escherichia coli, Appl. Microbiol. Biotechnol. 88 (2010) 167–175. 4. Oren, Z., Lerman, J. C., Gudmundsson, G. H., Agerberth, B. & Shai, Y. (1999). Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity. Biochem J 341, 501–513. 5. Jenssen, H., Hamill, P. & Hancock, R. E. (2006). Peptide antimicrobial agents. Clin Microbiol Rev 19, 491–511. 6. Reddy KVR, Yedery RD, Aranha C (2004) Antimicrobial peptides: premises and promises. Int J Antimicrobial Agents 24:536–547 7. Hong IP, Lee SJ, Kim YS, Choi SG (2007) Recombinant expression of the human cathelicidin (hCAP18/LL-37) in Pichia pastoris. Biotechnol Lett 29:73–78 8. Li Y, Li X, Wang G (2006) Cloning, expression, isotope labeling, and purification of human antimicrobial peptide LL-37 in Escherichia coli for NMR studies. Protein Expr Purif 47:498–505 9. Turner J, Cho Y, Dinh NN, Waring AJ (1998) Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils. Antimicrob Agents Chemother 42:2206–2214