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Part:BBa_K1228009

Designed by: Zhang SW   Group: iGEM13_HZAU-China   (2013-09-10)
Revision as of 09:48, 27 September 2013 by LeXiong (Talk | contribs)

38aa and 25aa fusion peptide with T1 terminator and Constitutive promoter veg

Human lysozyme (hLZ), the major protein in breast milk, exhibits microbicidal activity to various degrees against several bacterial strains. The HLH peptide(38Aminoacid peptides) and its N-terminal helix (H1) were the most potent bactericidal to bacteria. Evidence shows that HLH peptide and its N-terminal helix (H1) kill bacteria by crossing the outer membrane of Gram-negative bacteria via self-promoted uptake and is able to dissipate the membrane-potential-dependent respiration of Gram-positive bacteria. Lactoferrin (Lf) is a multifunctional member of the transferrin. Lf is found at the mucosal surface where it functions as a prominent component of the first line of the host defense system against infection and inflammation. This protein has a broad spectrum of anti-infection and anti-inflammatory function. Also, lactoferrin has a broad anti-bacterial range and strong anti-bacterial activity.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//chassis/prokaryote/bsubtilis
Parameters
n/a38aa and 25aa fusion peptide with T1 terminator and Constitutive promoter veg