Coding
Part:BBa_K902030
Designed by: Emily Hicks Group: iGEM12_Calgary (2012-10-02)
Revision as of 00:58, 4 October 2012 by Kevinm.huie (Talk | contribs)
Manganese homeostatic regulation (mntR)
The mntR metalloregulatory protein is native to the Escherichia coli K-12 strain. This transcriptional regulator is found to observe the level of manganese and responds accordingly. The structure of this protein consists of a metal-binding domain that will respond in the presence of manganese and repress the small RNA gene mntS. Lack of mntS will then repress the manganese ion transporter (mntH) as 42-amino-acid protein forms. When this protein membrane is repress the bacteria cannot gained the needed manganese. It is also found that the mntR positively regulates the mntP a putative efflux pump that regulates the intracellular level of manganese.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 58
[edit]
Categories
Parameters
None |