Regulatory
nrdP
Part:BBa_K847211
Designed by: Bryce Bajar, Chris Jackson, Debha Amatya, Jason Hu, Ben Geilich Group: iGEM12_Stanford-Brown (2012-07-24)
nrd operon promoter
Under construction.
Usage and Biology
The nrd operon in E. coli expresses ribonucleotide reductase, an enzyme that reduces ribonucleotides into deoxyribonucleotides and is involved in bacterial cell cycle (Sun 1994). The promoter region is highly regulated and contains several DnaA boxes, indicating that activity is partly affected by initiation of DNA replication (Messer 2002). The promoter for this operon was found to begin activation during initiation of DNA replication and is cell-cycle dependent (Sun 1992).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
//chassis/prokaryote/ecoli
//promoter
//promoter
biology | |
control |