Composite
Part:BBa_K887004:Design
Designed by: WU, CHENG-HSUAN Group: iGEM12_NCTU_Formosa (2012-09-21)
Plac+alsS+ilvC+ilvD(each preceded by own zinc-finger and RBS)+Ptet+B0032+kivD+B0015
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 7718
Illegal XhoI site found at 6049 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 6938
Illegal AgeI site found at 3158
Illegal AgeI site found at 4143 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 2744
Illegal BsaI site found at 5835
Illegal BsaI site found at 6092
Illegal BsaI.rc site found at 836
Illegal BsaI.rc site found at 1430
Illegal BsaI.rc site found at 3563
Design Notes
We add zinc fingers in front of enzymes in the circuit, and therefore the enzymes could bind the DNA program in order. It help enhance the efficiency of isobutanol production .
Source
The circuit is optimized from 2011 NCTU_FORMOSA.