Coding
FadA

Part:BBa_K861400

Designed by: Kuanwei Sheng   Group: iGEM12_WHU-China   (2012-08-16)
Revision as of 11:44, 16 August 2012 by Shinkwee (Talk | contribs)

For a E.coli to degrade fatty acid, at least four enzymes – FadA, FadB, FadD, FadE and transporter—FadL are needed. Long chain fatty acids(FAs) are firstly being imported by the transmembrane protein FadL. After FAs get into cells, they will be added a CoA by inner membrane-associated FadD (acyl-CoA synthase). β-oxidation is initiated by FadE(acyl-CoA dehydrogenase), which will convert acyl-CoA into enoyl-CoA. The followed cycles of hydration, oxidation, and thiolytic cleavage are carried out by tetrameric complex consisting of two FadA and two FadB proteins.

[edit]
Categories
//cds/enzyme
//chassis/prokaryote/ecoli
//direction/forward
Parameters
n/aFadA protein coding sequence for fatty acid degradation