Coding
FadA
Part:BBa_K861400
Designed by: Kuanwei Sheng Group: iGEM12_WHU-China (2012-08-16)
Revision as of 11:41, 16 August 2012 by Shinkwee (Talk | contribs) (New page: For a E.coli to degrade fatty acid, at least four enzymes – FadA, FadB, FadD, FadE and transporter—FadL are needed. Long chain fatty acids are firstly being imported by the transmembr...)
For a E.coli to degrade fatty acid, at least four enzymes – FadA, FadB, FadD, FadE and transporter—FadL are needed. Long chain fatty acids are firstly being imported by the transmembrane protein FadL. After FAs get into cells, they will be added a CoA by inner membrane-associated FadD (acyl-CoA synthase). β-oxidation is initiated by FadE(acyl-CoA dehydrogenase), which will convert acyl-CoA into enoyl-CoA. The followed cycles of hydration, oxidation, and thiolytic cleavage are carried out by tetrameric complex consisting of two FadA and two FadB proteins.
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Categories
Parameters
//cds/enzyme
//chassis/prokaryote/ecoli
//direction/forward
//chassis/prokaryote/ecoli
//direction/forward
| n/a | FadA protein coding sequence for fatty acid degradation |