Composite
Part:BBa_K676008:Design
Designed by: Kheng Tee Ng Group: iGEM11_UCL_London (2011-09-17)
GyrA cassette
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 1819
Illegal BglII site found at 2764 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 253
Illegal AgeI site found at 929
Illegal AgeI site found at 986
Illegal AgeI site found at 1625
Illegal AgeI site found at 2381
Illegal AgeI site found at 2749 - 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 269
Illegal SapI.rc site found at 277
Illegal SapI.rc site found at 1736
Design Notes
The wild type Gyr A ORF has a Pst 1 restriction site at the 1212th bp position so site directed mutagenesis has been carried out to remove the restriction site.
Source
Gyr A gene is obtained from E.coli genome.