Regulatory

Part:BBa_K639002:Experience

Designed by: Espen Bang Leistad   Group: iGEM11_NTNU_Trondheim   (2011-08-26)
Revision as of 08:57, 26 August 2011 by Espenban (Talk | contribs) (→‎Applications of BBa_K639002)

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Applications of BBa_K639002

Previous studies have shown that the rrnB P1 promoter is downregulated by ppGpp [1], which is an alarmone involved in the stringent response in bacteria. Our project involved using the rrnB P1 promoter as a stress-sensor, where it would stop expressing an inhibitor for a second promoter, thus giving a signal.


[1] Magnusson, Lisa U., Farewell, Anne, Nyström, Thomas: "ppGpp: a global regulator in Escherichia Coli", 2005

User Reviews

UNIQ70ccf03c31ac9464-partinfo-00000000-QINU UNIQ70ccf03c31ac9464-partinfo-00000001-QINU