Regulatory

Part:BBa_K339006

Designed by: Christopher Tang   Group: iGEM10_Calgary   (2010-10-25)
Revision as of 05:29, 30 October 2010 by H.dastidar (Talk | contribs) (→‎Usage and Biology)

CpxP Promoter

CpxP promoter, periplasmic stress activated promoter

Usage and Biology

CpxP is a member of the Cpx regulon which docks on to CpxA, a transmembrane protein normally. But in the case of envelope stress causing protein misfolding in the periplasmic space, CpxP detaches from CpxA and attaches to the misfolded protein in the periplasmic space.

http://i872.photobucket.com/albums/ab287/iGEMCalgary_2010/Cpxresponse.png This diagram illustrated that the CpxP promoter is the most sensitive in the stress regulon. CpxP is followed by CpxR and DegP respectively. These were selected because they are some of the most sensitive in the periplasmic stress detection pathways

Functional Parameters

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Categories
Parameters
None