Plasmid
Part:BBa_K364332:Experience
Designed by: Endre Károly Kristóf Group: iGEM10_Debrecen-Hungary (2010-10-20)
This experience page is provided so that any user may enter their experience using this part.
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Ligand
PXR is activated by a large number of endogenous and exogenous chemicals including steroids, antibiotics, antimycotics, bile acids, hyperforin, a constituent of the herbal antidepressant St. John's Wort, and many other herbal compounds.
PXR is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.
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