Coding

Part:BBa_K364314:Experience

Designed by: Lior Malka   Group: iGEM10_Debrecen-Hungary   (2010-10-01)
Revision as of 18:15, 25 October 2010 by Lityupix (Talk | contribs) (→‎Applications of BBa_K364314)

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Physiological functions of NHR8

NHR8 is required for gut function and may respond to the food signal.

The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine.

This resembles the regulation of protective metabolic enzymes by xenobiotic-sensing nuclear receptors. NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3.

Possible applications of NHR8 LBD

This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules.

Applications of BBa_K364314

User Reviews

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