Composite
Part:BBa_K5089006:Design
Designed by: Camille Prefontaine Group: iGEM24_UManitoba (2024-09-29)
CLE-CsgA-LCI
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 226
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This expression system is codon optimized for expression in E.coli.
Source
CLE is a cutinase from Cryptococcus sp. strain S-2, previously shown to cleave carbon-chain ester substrates [1]. LCI (Liquid Chromatography peak I) is a binding peptide for polystyrene, polypropylene and polylactic acid [2]. CsgA is a protein component of E.coli biofilms, which can be used as an anchor to surface display proteins [3].