Coding
Part:BBa_K4437502:Design
Designed by: Marian Grell Group: iGEM22_Calgary (2022-10-12)
B0030-FLAG-phasin-HlyA (E. coli)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This sequence was designed for experiments comparing RBS strength and resulting FLAG-phasin-HlyA expression levels, with the purpose of improving the expression system to increase phasin yields. Specifically, the aim of this part was to increase, or improve, phasin expression as compared to the original BBa_K2260002 part. As such, this part was designed to produce the weakest expression levels of the four RBS-FLAG-phasin-HlyA parts in our part collection.
Source
This part is based on the BBa_K2260002 part from the University of Calgary's 2017 iGEM team. The phasin (PhaP) gene is from R. eutropha, the HlyA tag is from E. coli, and the T7 promoter is from the T7 bacteriophage.