Coding

Part:BBa_K3962350

Designed by: Siheng Li   Group: iGEM21_Leiden   (2021-10-13)
Revision as of 08:07, 16 October 2021 by SihengLi (Talk | contribs)


HOK - Toxin in Hok/Sok

Sok is the antitoxin of the Hok/Sok toxin-antitoxin system. The Hok/Sok is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The Sok transcript can bind to a homologous region onHok mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived Hok toxin from the parent cell. Due to the short half-life of the Sok antitoxin, daughter cells inherit only small amounts and it is quickly degraded.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None