Composite
T7RNAP-VVD
Part:BBa_K4055001
Designed by: Tianzuo Zeng Group: iGEM21_Yucai_SZ (2021-10-21)
J23106-RBS-T7 RNA polymerase N 1~179-Vvd-RBS-Vvd-T7 RNA polymerase C 180~883
This is a similar design to Part:BBa_K3628024 but split the T7RNAP between aa179 and aa180. The split T7RNAP has little activity in a dark environment. When the two segments were exposed to blue light, they will bind together due to the photodimerization of VVD domain and exhibit full RNA polymerase activity.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 7
Illegal NheI site found at 30 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 798
Illegal AgeI site found at 1026
Illegal AgeI site found at 1343
Illegal AgeI site found at 1571 - 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
//cds/enzyme/rnap
//rnap/bacteriophage/t7
//rnap/bacteriophage/t7
None |