Coding
Part:BBa_K3815008
Designed by: Hiroto Koga Group: iGEM21_Kyoto (2021-10-16)
LL37-Mxe GryA intein-PT-linker-His tag
This part is made of Hist tag for the peptide production. After producing peptide with His tag, it is recovered by Ni chromatography. Finally, adding DTT to it, we cut the N terminal of Mxe GyrA intein. Then, we can get the targeted protein.In this part, the purpose protein is LL37 derived from human. This is antimicrobial peptide that can inhibit the growth of both gram-negative bacteria and gram-positive bacteria. In our experiment, we used it to kill the bacteria in the vase water.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 637
Illegal AgeI site found at 130
Illegal AgeI site found at 331
Illegal AgeI site found at 765 - 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |