Coding

Part:BBa_K3846008

Designed by: Marcel Arvid Zimmeck   Group: iGEM21_Hamburg   (2021-10-12)
Revision as of 17:07, 12 October 2021 by Registry (Talk | contribs)

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Germacrene A hydroxylase

Involved in the biosynthesis of germacrene-derived sesquiterpene lactones (PubMed:30468448).

Component of the parthenolide biosynthetic pathway; parthenolide and conjugates are promising anti-cancer drugs highly active against colon cancer cells (PubMed:30468448).

Catalyzes three consecutive oxidations of germacrene A to produce germacrene A acid (PubMed:24704560).

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None