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Part:BBa_K3838888
Designed by: Siyang Yu Group: iGEM21_SZU-China (2021-08-30)
partinfoBBa_K3838888 shortpartinfo
The overproduction of Superoxide dismutase (SOD) and reactive oxygen species (ROS) is considered to be one of the pathogenesis of IBD. The use of SOD can significantly reduce the peroxidation reaction in the inflamed colon. Studies have shown that the decreased expression of CuZn-SOD has been observed in IBD patients. SOD can not be directly treated, so carrier transport is needed. Therefore, we selected for heteroexpression of superoxide dismutase (SOD) gene from LACTObacillus casei Lc18. In a team project, SOD related parts are composed as follows J23100 promoter +RBS+SOD+ HIS tag +Signal peptide+T7 terminator
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