Part:BBa_K3989012
EsaR regulator
EsaR is a regulator protein which regulates the promoter of a bacterial Quorum Sensing system. By interacting with the Quorum Sensing molecules(a class of molecules called AHL.In our project, the molecule is called 3OC6HSL since it shows a higher sensitivity), it can either act as a repressor or an activator depending on the location of the promoter it binds.
How it works
In the Pesa promoter controlled Quorum Sensing system, EsaR acts as a regulator that can bind to a specific site of the promoter Pesa. Depending on the different types of the Pesa(PesaR and PesaS), EsaR can be either a repressor(for PesaR) or an activator(for PesaR). The detailed mechanism is shown below:
From the figure we can see that, the EsaR protein binds to a specific site called the
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