RNA
gard-337
Part:BBa_K3714000
Designed by: Yuxin Lu Group: iGEM21_SJTU-BioX-Shanghai (2021-08-30)
Gardiquimod biosensor 337
A newly found self-cleaving aptazyme, which can keep itself stable when the gardiquimod in existence, and catalyze the self-cleavage reaction in the absence of gardiquimod. This part could be used as a switch for gene expression controlled by gardiquimod.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
//rna/aptazyme
efficiency | 10 μM gardiquimod inhibits 94.4% cleavage[1] |