Coding
Part:BBa_K3381002
Designed by: Jeriann Hsiao Group: iGEM20_Waterloo (2020-10-20)
Mst-CopC (copper-binding)
Mst-CopC is a copper binding protein with a single binding site that preferentially binds Cu(II). Published binding affinities for Mst-CopC did not include the variant present in Methylosinus trichosporium; however, we determined its interaction energy was -540.6373 kJ/mol using molecular dynamics. Mst-CopC binds Cu(II) with a “distorted square pyramidal geometry with H23, H107, D105, and the amino terminus comprising the planar ligands and a water molecule serving as the axial ligand” (Lawton, Kenney, Hurley, & Rosenzweig, 2016).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
None |