Coding

Part:BBa_K3381002

Designed by: Jeriann Hsiao   Group: iGEM20_Waterloo   (2020-10-20)
Revision as of 01:27, 24 October 2020 by Jlhsiao (Talk | contribs)

Mst-CopC (copper-binding)

Mst-CopC is a copper binding protein with a single binding site that preferentially binds Cu(II). Published binding affinities for Mst-CopC did not include the variant present in Methylosinus trichosporium; however, we determined its interaction energy was -540.6373 kJ/mol using molecular dynamics. Mst-CopC binds Cu(II) with a “distorted square pyramidal geometry with H23, H107, D105, and the amino terminus comprising the planar ligands and a water molecule serving as the axial ligand” (Lawton, Kenney, Hurley, & Rosenzweig, 2016).

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None