Coding
Part:BBa_K3582203
Designed by: Avadhoot Jadhav, Merrin Vincent Group: iGEM20_IISER-Pune-India (2020-10-22)
Inhibitory Sequence 1 for EPCR-PfEMP1 Interaction (4V3D)
The following characteristic properties are observed in the inhibitory peptide sequence:
- 1] Interaction Energy:-5.96088 kcal/mol
- 2] Stability Value: 7.38979 dG units
This bio brick synthesizes the inhibitory peptide sequence that is believed to bind more efficiently as Compared to the wild type sequence. The peptide sequence is built using saturated mutagenesis. In this particular mutant sequence, the amino acid of the Wild type sequence-Glutamic acid is replaced with leucine. As a result, an upgradation in its interactive properties is observed that is thought to improve its binding strength.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |