Part:BBa_K3506007
CLB2 promoter
This part is the CLB2 promoter which is -829 to -365 nt relative to CLB2 ATG on the genome of Saccharomyces cerevisiae BY4741. CLB2 promoter is the promoter of the G2/mitotic-specific cyclin-2(CLB2) which accumulates steadily during G2 and is abruptly destroyed at mitosis. CLB2 interacts with the CDC2 protein kinase to form maturation-promoting factor(MPF) and is essential for the control of the cell cycle at the G2/M (mitosis) transition.Previous studies have revealed that CLB2 promoter can regulate the transcription of its downstream gene periodically. Under the control of CLB2 promoter, the downstream gene starts to transcript in the S phase, reaches a peak at the G2/M transition, and rapidly degrades at the end of the M phase.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 229
- 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 203
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
None |